Tumor Necrosis Factor Inhibition in the Acute Management of Traumatic Optic Neuropathy
Investigative Ophthalmology & Visual Science2018Vol. 59(7), pp. 2905–2905
Citations Over TimeTop 10% of 2018 papers
Brian C. Tse, Galina Dvoriantchikova, Wensi Tao, Ryan A. Gallo, John Y. Lee, Steven Pappas, Roberta Brambilla, Dmitry Ivanov, David T. Tse, Daniel Pelaez
Abstract
Treatment with etanercept significantly reduced retinal damage and improved visual function in both animal models of TON. These findings suggest that reducing TNF activity in injured optic nerves constitutes an effective therapeutic approach in an acute setting.
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