Rabbit Model of Intra-Arterial Chemotherapy Toxicity Demonstrates Retinopathy and Vasculopathy Related to Drug and Dose, Not Procedure or Approach
Investigative Ophthalmology & Visual Science2019Vol. 60(4), pp. 954–954
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Anthony B. Daniels, Michael T. Froehler, Amy H. Nunnally, Janene Pierce, I. Bozic, Cameron Stone, Pranav R. Santapuram, Yuankai K. Tao, Kelli L. Boyd, Lauren E. Himmel, Sheau‐Chiann Chen, Liping Du, Debra L. Friedman, Ann Richmond
Abstract
IAC toxicity appears to be related to the specific drug being used and is dose-dependent, rather than related to the IAC procedure itself or the specific technique selected. These rabbit findings are corroborated by our clinical findings in patients.
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