Isotretinoin Impairs the Secretory Function of Meibomian Gland Via the PPARγ Signaling Pathway
Investigative Ophthalmology & Visual Science2022Vol. 63(3), pp. 29–29
Citations Over TimeTop 10% of 2022 papers
Abstract
Isotretinoin does not cause a significant atrophy of the acinus and a significant change of FoxO1 expression in the meibomian gland. Isotretinoin causes meibomian gland dysfunction, affecting meibocyte differentiation and qualitative and quantitative changes in the meibum, through PPARγ pathway.
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