Potential Structural Biomarkers in 3D Images Validated by the First Functional Biomarker for Early Age-Related Macular Degeneration – ALSTAR2 Baseline
Investigative Ophthalmology & Visual Science2024Vol. 65(2), pp. 1–1
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Sohaib Fasih‐Ahmad, Ziyuan Wang, Zubin Mishra, Charles Vatanatham, Mark E. Clark, Thomas A. Swain, Christine A. Curcio, Cynthia Owsley, Srinivas R. Sadda, Zhihong Hu
Abstract
RMDA is correlated with the status of outer retinal bands in early and intermediate AMD eyes, particularly, the status of the IZ. This correlation is consistent with a previous analysis of only foveal B-scans and is biologically plausible given that retinoid availability, involving transfer at the interface attributed to the IZ, is rate-limiting for RMDA.
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