0 references
Identification of COL4A2 as a Biomarker of Extracellular Matrix Remodeling and Vascular Scaffold in Choroid for Myopia
Investigative Ophthalmology & Visual Science2026Vol. 67(3), pp. 31–31
Abstract
Type IV collagen is a key ECM in construction of the choroidal vascular lumen. COL4A2 is downregulated in FDM choroid, and suppression of COL4A2 impairs the choroid vascular scaffold and promotes myopia shift with decreased choroidal thickness.