Comparison and calibration of transcriptome data from RNA-Seq and tiling arrays
BMC Genomics2010Vol. 11(1), pp. 383–383
Citations Over TimeTop 10% of 2010 papers
Ashish Agarwal, David Koppstein, Joel Rozowsky, Andrea Sboner, Lukas Habegger, LaDeana Hillier, Rajkumar Sasidharan, V Reinke, R Waterston, Mark Gerstein
Abstract
Tiling arrays effectively detect transcript expression levels at a low cost for many species while RNA-Seq provides greater accuracy in several regards. Researchers will need to carefully select the technology appropriate to the biological investigations they are undertaking. It will also be important to reconsider a comparison such as ours as sequencing technologies continue to evolve.
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