OligoRAP – an Oligo Re-Annotation Pipeline to improve annotation and estimate target specificity
BMC Proceedings2009Vol. 3(S4), pp. S4–S4
Citations Over TimeTop 17% of 2009 papers
Pieter BT Neerincx, Han Rauwerda, Haisheng Nie, Martien A. M. Groenen, Timo M. Breit, Jack A. M. Leunissen
Abstract
As microarrays are designed on incomplete data, it is important to update probe annotation and check target specificity regularly. OligoRAP provides both and due to its design based on BioMoby web services it can easily be embedded as an oligo annotation engine in customised applications for microarray data analysis. The dramatic difference in updated annotation and target specificity for the ARK-Genomics 20 K chicken array as compared to the original data emphasises the need for regular updates.
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