Trans-generational epigenetic regulation of C. elegans primordial germ cells
Epigenetics & Chromatin2010Vol. 3(1), pp. 15–15
Citations Over TimeTop 10% of 2010 papers
Hirofumi Furuhashi, Teruaki Takasaki, Andreas Rechtsteiner, Tengguo Li, Hiroshi Kimura, Paula M Checchi, Susan Strome, William G. Kelly
Abstract
Our data suggest a model in which MES-4 helps to maintain an 'epigenetic memory' of transcription that occurred in germ cells of previous generations, and that MES-4 and its epigenetic product are essential for normal germ cell development.
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