Extracellular heat shock protein 70 inhibits tumour necrosis factor-α induced proinflammatory mediator production in fibroblast-like synoviocytes
Arthritis Research & Therapy2008Vol. 10(2), pp. R41–R41
Citations Over TimeTop 10% of 2008 papers
Xinjing Luo, Xiaoxia Zuo, Yaou Zhou, Bing Zhang, Yongzhong Shi, Meidong Liu, Kangkai Wang, Darrius McMillian, Xianzhong Xiao
Abstract
Extracellular HSP70 has an anti-inflammatory effect on RA by downregulating production of IL-6, IL-8 and MCP-1 in fibroblast-like synoviocytes, which is mediated through inhibited activation of the MAPKs and NF-kappaB signal pathways.
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