Mapping similarities in mTOR pathway perturbations in mouse lupus nephritis models and human lupus nephritis
Arthritis Research & Therapy2008Vol. 10(6), pp. R127–R127
Citations Over TimeTop 16% of 2008 papers
Padmalatha S. Reddy, Holly Legault, Joseph P. Sypek, Mark J Collins, Elizabeth Goad, Samuel J. Goldman, Wei Liu, Stuart Murray, Andrew J. Dorner, Margot O’Toole
Abstract
Our findings implicate the mTOR pathway as a critical contributor to human lupus. This broad pathway-based approach to understanding the similarities in, and differences between, animal models and human diseases may have broader utility.
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