Arthritogenic T cell epitope in glucose-6-phosphate isomerase-induced arthritis
Arthritis Research & Therapy2008Vol. 10(6), pp. R130–R130
Citations Over TimeTop 24% of 2008 papers
Keiichi Iwanami, Isao Matsumoto, Yôko Tanaka, Asuka Inoue, Daisuke Goto, Satoshi Ito, Akito Tsutsumi, Takayuki Sumida
Abstract
Human GPI325-339 was identified as a major epitope in GPI-induced arthritis, and proved to have the potential to induce polyarthritis. Understanding the pathological mechanism of arthritis induced by an immune reaction to a single short peptide could help elucidate the pathogenic mechanisms of autoimmune arthritis.
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