Characteristics of repair tissue in second-look and third-look biopsies from patients treated with engineered cartilage: relationship to symptomatology and time after implantation
Arthritis Research & Therapy2008Vol. 10(6), pp. R132–R132
Citations Over TimeTop 10% of 2008 papers
Paola Brun, Sally C. Dickinson, Barbara Zavan, Roberta Cortivo, Anthony P. Hollander, Giovanni Abatangelo
Abstract
The study indicates that, in asymptomatic patients after chondrocyte implantation, regenerated tissue undergoes a process of maturation that in the majority of cases takes longer than 18 months for completion and leads to hyaline tissue and not fibrous cartilage. Persistence of symptoms might reflect the presence of a nonhyaline cartilage repair tissue.
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