Candidate autoantigens identified by mass spectrometry in early rheumatoid arthritis are chaperones and citrullinated glycolytic enzymes
Arthritis Research & Therapy2009Vol. 11(2), pp. R38–R38
Citations Over TimeTop 10% of 2009 papers
Vincent Goëb, Marlène Thomas-L'Otellier, Romain Daveau, Roland Charlionet, Patrice Fardellone, Xavier Le Loët, François Tron, Danièle Gilbert, Olivier Vittecoq
Abstract
Two categories of antigens, enzymes of the glycolytic family and molecular chaperones are also targeted by the early untreated RA autoantibody response. For some of them, and notably the FUSE-BPs, citrullination is involved in the immunological tolerance breakdown observed earlier in RA patients. Autoantibodies recognizing a citrullinated peptide from FUSE-BP may enhance the sensibility for RA of the currently available anti-CCP2 test.
Related Papers
- → Trace elements and disease activity score in patients with rheumatoid arthritis(2003)10 cited
- Rheumatoid arthritis and astercantha longifolia.(1999)
- [Radiosynoviorthese in the treatment of patients with rheumatoid arthritis].(1990)
- → Functional activity of phagocytic cells in patients with rheumatoid arthritis in combination with arterial hypertension: changes in the treatment process(2019)