Replication of recently identified systemic lupus erythematosus genetic associations: a case–control study
Arthritis Research & Therapy2009Vol. 11(3), pp. R69–R69
Citations Over TimeTop 1% of 2009 papers
Marian Suarez-Gestal, Manuel Calaza, Emõke Endreffy, R Pullmann, Josep Ordi‐Ros, Gian Domenico Sebastiani, Š Rùzicková, María José Santos, Chryssa Papasteriades, Maurizio Marchini, Fotini N. Skopouli, Ana Suárez, Francisco J. Blanco, Sandra D’Alfonso, Marc Bijl, Patrícia Carreira, Torsten Witte, S. Migliaresi, Juan J. Gómez‐Reino, Antonio González
Abstract
Our results confirm nine SLE loci. For six of them, TYK2, MECP2, 1q25.1, PXK, BANK1 and KIAA1542, this replication is important. The other three loci, ITGAM, STAT4 and C8orf13-BLK, were already clearly confirmed. Our results also suggest that MECP2 association has no influence in the sex bias of SLE, contrary to what has been proposed. In addition, none of the other associations seems important in this respect.