Monocyte surface expression of Fcγ receptor RI (CD64), a biomarker reflecting type-I interferon levels in systemic lupus erythematosus
Arthritis Research & Therapy2010Vol. 12(3), pp. R90–R90
Citations Over TimeTop 12% of 2010 papers
Yi Li, Pui Y. Lee, Erinn S. Kellner, Matthew Paulus, Juliana Switanek, Yuan Xu, Haoyang Zhuang, Eric S. Sobel, Mark S. Segal, Minoru Satoh, Westley H. Reeves
Abstract
Expression of CD64 on circulating monocytes is IFN-I inducible and highly correlated with ISG expression. Flow-cytometry analysis of CD64 expression on circulating monocytes is a convenient and rapid approach for estimating IFN-I levels in SLE patients.
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