An in vivoinvestigation of the initiation and progression of subchondral cysts in a rodent model of secondary osteoarthritis
Arthritis Research & Therapy2012Vol. 14(1), pp. R26–R26
Citations Over TimeTop 10% of 2012 papers
David D. McErlain, Veronica Ulici, Mark Darling, Joseph S. Gati, Vasek Pitelka, Frank Beier, David W. Holdsworth
Abstract
This study provides insight into the mechanisms leading to SBC formation in knee OA. The expansion of these lesions is due to stress-induced bone resorption from the incurred mechanical instability. Therefore, we suggest these lesions can be more accurately described as a form of OA-induced osteonecrosis, rather than 'subchondral cysts'.
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