Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus
Arthritis Research & Therapy2012Vol. 14(6), pp. R243–R243
Citations Over TimeTop 12% of 2012 papers
Jack Hutcheson, Kamala Vanarsa, Anna Bashmakov, Simer Grewal, Deena Sajitharan, Betty Chang, Joseph J. Buggy, Xin Zhou, Yong Du, Anne B. Satterthwaite, Chandra Mohan
Abstract
These findings suggest that partial crippling of cell signaling in B cells and antigen presenting cells (APCs) may be a viable alternative to total depletion of these cells as a therapeutic modality for lupus.
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