Increased frequency of Th17 cells in systemic sclerosis is related to disease activity and collagen overproduction
Arthritis Research & Therapy2014Vol. 16(1), pp. R4–R4
Citations Over TimeTop 10% of 2014 papers
Abstract
SSc progression might be linked to expansion of circulating Th17 cells and increased infiltration of IL-17⁺ cells in skin. Th17-derived IL-17 is involved in fibroblast growth and collagen production. IL-17 blocking antibody may be a useful tool for intervention in the fibrotic course of SSc.
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