Exosomes from IL-1β stimulated synovial fibroblasts induce osteoarthritic changes in articular chondrocytes
Arthritis Research & Therapy2014Vol. 16(4), pp. R163–R163
Citations Over TimeTop 10% of 2014 papers
Tomohiro Kato, Shigeru Miyaki, Hiroyuki Ishitobi, Yoshihiro Nakamura, Tomoyuki Nakasa, Martin Lotz, Mitsuo Ochi
Abstract
Exosomes from IL-1β stimulated SFB induce OA-like changes both in vitro and in ex vivo models. Exosomes represent a novel mechanism by which pathogenic signals are communicated among different cell types in OA-affected joints.
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