Intrinsic molecular signature of breast cancer in a population-based cohort of 412 patients
Breast Cancer Research2006Vol. 8(4), pp. R34–R34
Citations Over TimeTop 10% of 2006 papers
Stefano Calza, Per Hall, Gert Auer, Judith Bjöhle, Sigrid Klaar, Ulrike Kronenwett, Edison T. Liu, Lance D. Miller, Alexander Ploner, Johanna Smeds, Jonas Bergh, Yudi Pawitan
Abstract
We found that the intrinsic molecular subtypes of breast cancer are broadly present in a diverse collection of patients from a population-based cohort in Sweden. The intrinsic gene set, originally selected to reveal stable tumor characteristics, was shown to have a strong correlation with progression-related properties such as grade, p53 mutation and genomic instability.
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