A divergent role for estrogen receptor-beta in node-positive and node-negative breast cancer classified according to molecular subtypes: an observational prospective study
Breast Cancer Research2008Vol. 10(5), pp. R74–R74
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Flavia Novelli, Michele Stanislaw Milella, Elisa Melucci, Anna Di Benedetto, Isabella Sperduti, Raffaele Perrone-Donnorso, Letizia Perracchio, Irene Venturo, Cecilia Nisticò, Alessandra Fabi, Simonetta Buglioni, Pier Giorgio Natali, Marcella Mottolese
Abstract
Our data indicated that, in contrast to node-negative patients, in node-positive breast cancer patients, ER-beta positivity appears to be a biomarker related to a more aggressive clinical course. In this context, further investigations are necessary to better assess the role of the different ER-beta isoforms.
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