Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression
Breast Cancer Research2003Vol. 6(2), pp. R92–109
Citations Over TimeTop 10% of 2003 papers
Abstract
We provide a resource of mouse mammary gene expression data for download or online analysis. Here we highlight the sequential induction of distinct apoptosis pathways in involution and the stimulation of immunomodulatory signals, which probably suppress the potentially damaging effects of a cellular inflammatory response while maintaining an appropriate antimicrobial and phagocytic environment.
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