Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients
Critical Care2011Vol. 15(2), pp. R99–R99
Citations Over TimeTop 10% of 2011 papers
Caroline Guignant, Alain Lepape, Xin Huang, Hakim Kherouf, Laure Denis, Françoise Poitevin, Christophe Malcus, A. Chéron, Bernard Allaouchiche, François Gueyffier, Alfred Ayala, Guillaume Monneret, Fabienne Venet
Abstract
These findings indicate that PD-1-related molecules may constitute a novel immunoregulatory system involved in sepsis-induced immune alterations. Results should be confirmed in a larger cohort of patients. This may offer innovative therapeutic perspectives on the treatment of this hitherto deadly disease.
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