Short-term effects of high-dose oral vitamin D3 in critically ill vitamin D deficient patients: a randomized, double-blind, placebo-controlled pilot study
Critical Care2011Vol. 15(2), pp. R104–R104
Citations Over TimeTop 10% of 2011 papers
Karin Amrein, Harald Sourij, Gerit Wagner, Alexander Höll, Thomas R. Pieber, Karl Heinz Smolle, Tatjana Stojaković, Christian Schnedl, Harald Dobnig
Abstract
This pilot study shows that a single oral ultra-high dose of cholecalciferol corrects vitamin D deficiency within 2 days in most patients without causing adverse effects like hypercalcemia or hypercalciuria. Further research is needed to confirm our results and establish whether vitamin D supplementation can affect the clinical outcome of vitamin D deficient critically ill patients. EUDRACT NUMBER: 2009-012080-34 GERMAN CLINICAL TRIALS REGISTER (DRKS): DRKS00000750.
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