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Serum soluble-Fas, inflammation and anemia in acute renal failure and critical illness

Critical Care2011Vol. 15(S2)

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MÂ Góes, MA Dalboni, Bmr Quinto, IJ Iizuka, JC Monte, OF Pavão dos Santos, VG Pereira, Marcelino de Souza Durão, MC Batista, Miguel Cendoroglo

Abstract

Soluble Fas (sFas) levels are associated with anemia and erythropoietin (Epo) hyporesponsiveness in chronic kidney disease. Anemia is also a common feature in patients with acute renal failure (ARF) and in critically ill patients. Therefore, it is possible that sFas levels are also associated with anemia and increased need for serum Epo levels in ARF and critical illness in order to maintain hemoglobin (Hgb) levels.

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