Worst Oxygenation Index during the first 24 hours of ventilation predicts mortality

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Abstract

The ratio of PaO2 to FiO2 (P/F ratio) is often used to classify patients with hypoxic respiratory failure, and is recommended in guidelines from a UK expert group [1] but does not take airway pressures into account. A study found that adjusting for PEEP did not affect the predictive ability of the P/F ratio [2]; however, the mean airway pressure (MAP) may be a better indicator of lung recruitment. The Oxygenation Index (OI = (FiO2×MAP)/PaO2)) includes an adjustment for MAP.

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