High frequency oscillatory ventilation compared with conventional mechanical ventilation in adult respiratory distress syndrome: a randomized controlled trial [ISRCTN24242669]
Critical Care2005Vol. 9(4), pp. R430–9
Citations Over TimeTop 10% of 2005 papers
Casper W. Bollen, Gijs T. J. van Well, Tony Sherry, Richard Beale, Sanjoy Shah, George Findlay, Mehran Monchi, Jean‐Daniel Chiche, Norbert Weiler, Cuno S.P.M. Uiterwaal, Adrianus J. van Vught
Abstract
No significant differences were observed, but this trial only had power to detect major differences in survival without oxygen or on ventilator. In patients with ARDS and higher baseline OI, however, there might be a treatment benefit of HFOV over CV. More research is needed to establish the efficacy of HFOV in the treatment of ARDS. We suggest that future studies are designed to allow for informative analysis in patients with higher OI.
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