Inflammatory and transcriptional roles of poly (ADP-ribose) polymerase in ventilator-induced lung injury
Critical Care2008Vol. 12(4), pp. R108–R108
Citations Over TimeTop 12% of 2008 papers
Je Hyeong Kim, Min Hyun Suk, Dae Wui Yoon, Hye Young Kim, Ki Hwan Jung, Eun Hae Kang, Sung Yong Lee, Sang Yeub Lee, In Bum Suh, Chol Shin, Jae Jeong Shim, Kwang Ho In, Se Hwa Yoo, Kyung Ho Kang
Abstract
Overactivation of PARP plays an important role in the inflammatory and transcriptional pathogenesis of VILI, and PARP inhibition has potentially beneficial effects on the prevention and treatment of VILI.
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