Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients
Critical Care2008Vol. 12(6), pp. R147–R147
Citations Over TimeTop 10% of 2008 papers
Philipp Kümpers, Alexander Lukasz, Sascha David, R. Horn, Carsten Hafer, Robert Faulhaber‐Walter, Danilo Fliser, Hermann Haller, Jan T. Kielstein
Abstract
A marked imbalance of the Ang-Tie system in favour of Ang-2 is present in critically ill medical patients. Our findings highlight the independent prognostic impact of circulating Ang-2 in critical illness. Ang-2 may be used as a readily available powerful predictor of outcome and may open new perspectives to individualise treatment in the ICU.
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