Increasing arterial blood pressure with norepinephrine does not improve microcirculatory blood flow: a prospective study
Critical Care2009Vol. 13(3), pp. R92–R92
Citations Over TimeTop 1% of 2009 papers
Arnaldo Dubín, Mario Omar Pozo, Christian A. Casabella, Fernando Pálizas, Gastón Murias, Miriam Moseinco, Vanina Siham Kanoore Edul, Fernando Pálizas, Elisa Estenssoro, Can İnce
Abstract
Patients with septic shock showed severe sublingual microcirculatory alterations that failed to improve with the increases in MAP with norepinephrine. Nevertheless, there was a considerable interindividual variation. Our results suggest that the increase in MAP above 65 mmHg is not an adequate approach to improve microcirculatory perfusion and might be harmful in some patients.
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