Incidence of propofol-related infusion syndrome in critically ill adults: a prospective, multicenter study
Critical Care2009Vol. 13(5), pp. R169–R169
Citations Over TimeTop 10% of 2009 papers
Russel J. Roberts, Jeffrey F. Barletta, Jeffrey Fong, Greg Schumaker, Philip J Kuper, Stella Papadopoulos, Dinesh Yogaratnam, E. J. C. Kendall, Renee C. Xamplas, Anthony T. Gerlach, Paul M. Szumita, Kevin E. Anger, Paul A. Arpino, Stacey A Voils, Philip Grgurich, Robin Ruthazer, John W. Devlin
Abstract
Despite using a conservative definition for PRIS, and only considering new-onset PRIS clinical manifestations, the incidence of PRIS slightly exceeds 1%. Future controlled studies focusing on evaluating whether propofol manifests the derangements of critical illness more frequently than other sedatives will need to be large. These studies should also investigate the mechanism(s) and risk factors for PRIS.
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