Organ failure and tight glycemic control in the SPRINT study
Critical Care2010Vol. 14(4), pp. R154–R154
Citations Over TimeTop 10% of 2010 papers
J. Geoffrey Chase, Christopher G. Pretty, Leesa Pfeifer, Geoffrey M. Shaw, Jean‐Charles Preiser, Aaron J. Le Compte, Jessica Lin, Darren Hewett, Katherine T. Moorhead, Thomas Desaive
Abstract
SPRINT TGC resolved organ failure faster, and for more patients, from similar admission and maximum SOFA scores, than conventional control. These reductions mirror the reduced mortality with SPRINT. The cTIB ≥0.5 metric provides a first benchmark linking TGC quality to organ failure. These results support other physiological and clinical results indicating the role tight, consistent TGC can play in reducing organ failure, morbidity and mortality, and should be validated on data from randomised trials.
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