A human functional protein interaction network and its application to cancer data analysis
Genome biology2010Vol. 11(5), pp. R53–R53
Citations Over TimeTop 1% of 2010 papers
Abstract
We have built a highly reliable functional interaction network upon expert-curated pathways and applied this network to the analysis of two genome-wide GBM and several other cancer data sets. The network patterns revealed from our results suggest common mechanisms in the cancer biology. Our system should provide a foundation for a network or pathway-based analysis platform for cancer and other diseases.
Related Papers
- → Conserved network motifs allow protein–protein interaction prediction(2004)189 cited
- → Inferrng protein-protein interactions using interaction network topologies(2006)6 cited
- → Characterization and Evolutionary Analysis of Protein–Protein Interaction Networks(2012)3 cited
- → Analysis of triangular motifs in protein interaction networks and their implications to protein ages and cancer genes(2017)
- → Analysis of triangular motifs in protein interaction networks and their implications to protein ages and cancer genes(2017)