A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains
Genome biology2013Vol. 14(7), pp. R82–R82
Citations Over TimeTop 1% of 2013 papers
Michelle M. Simon, Simon Greenaway, Jacqueline K. White, Helmut Fuchs, Valérie Gailus‐Durner, Sara Wells, Tania Sorg, Kim Wong, Elodie Bedu, Elizabeth J. Cartwright, Romain Dacquin, Sophia Djebali, Jeanne Estabel, Jochen Graw, Neil J. Ingham, Ian J. Jackson, Andreas Lengeling, Silvia Mandillo, Jacqueline Marvel, Hamid Méziane, Frédéric Preitner, Oliver Puk, Michel J. Roux, David J. Adams, Sarah Atkins, Abdel Ayadi, Lore Becker, Andrew Blake, Debra Brooker, Heather Cater, Marie‐France Champy, Roy Combe, Petr Danecek, Armida Di Fenza, Hilary Gates, Anna-Karin Gerdin, Elisabetta Golini, John M. Hancock, Wolfgang Hans, Sabine M. Hölter, Tertius Hough, Pierre Jurdic, Thomas Keane, Hugh W. Morgan, Werner Müller, Frauke Neff, George Nicholson, Bastian Pasche, Laura-Anne Roberson, Jan Rozman, Mark Sanderson, Luís Santos, Mohammed Selloum, Carl Shannon, Anne Southwell, Glauco P. Tocchini‐Valentini, Valerie E. Vancollie, Henrik Westerberg, Wolfgang Wurst, Min Zi, Binnaz Yalcin, Ramiro Ramírez‐Solis, Karen P. Steel, Ann‐Marie Mallon, Martin Hrabě de Angelis, Yann Hérault, Steve D. M. Brown
Abstract
Comparison of C57BL/6J and C57BL/6N demonstrates a range of phenotypic differences that have the potential to impact upon penetrance and expressivity of mutational effects in these strains. Moreover, the sequence variants we identify provide a set of candidate genes for the phenotypic differences observed between the two strains.
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