Metabolome in schizophrenia and other psychotic disorders: a general population-based study
Genome Medicine2011Vol. 3(3), pp. 19–19
Citations Over TimeTop 10% of 2011 papers
Matej Orešič, Jing Tang, Tuulikki Seppänen‐Laakso, Ismo Mattila, Suoma Saarni, Samuli I. Saarni, Jouko Lönnqvist, Marko Sysi‐Aho, Tuulia Hyötyläinen, Jonna Perälä, Jaana Suvisaari
Abstract
Our findings suggest that specific metabolic abnormalities related to glucoregulatory processes and proline metabolism are specifically associated with schizophrenia and reflect two different disease-related pathways. Metabolomics, which is sensitive to both genetic and environmental variation, may become a powerful tool in psychiatric research to investigate disease susceptibility, clinical course, and treatment response.
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