Serum metabolomic profile as a means to distinguish stage of colorectal cancer
Genome Medicine2012Vol. 4(5), pp. 42–42
Citations Over TimeTop 10% of 2012 papers
Farshad Farshidfar, Aalim M. Weljie, Karen Kopciuk, W D Buie, Anthony R. MacLean, Elijah Dixon, Francis Sutherland, Andrea Molckovsky, Hans J. Vogel, Oliver F. Bathe
Abstract
In CRC, the serum metabolomic profile changes markedly with metastasis, and site of disease also appears to affect the pattern of circulating metabolites. This novel observation may have clinical utility in enhancing staging accuracy and selecting patients for surgical or medical management. Additional studies are required to determine the sensitivity of this approach to detect subtle or occult metastatic disease.
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