Dosage compensation is less effective in birds than in mammals
Journal of Biology2007Vol. 6(1), pp. 2–2
Citations Over TimeTop 1% of 2007 papers
Yuichiro Itoh, Esther Melamed, Xia Yang, Kathy Kampf, Susanna Wang, Nadir Yehya, Atila van Nas, Kirstin Replogle, Mark R. Band, David F. Clayton, Eric E. Schadt, Aldons J. Lusis, Arthur P. Arnold
Abstract
Birds represent an unprecedented case in which genes on one sex chromosome are expressed on average at constitutively higher levels in one sex compared with the other. Sex-chromosome dosage compensation is surprisingly ineffective in birds, suggesting that some genomes can do without effective sex-specific sex-chromosome dosage compensation mechanisms.
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