Equine mesenchymal stem cells from bone marrow, adipose tissue and umbilical cord: immunophenotypic characterization and differentiation potential
Stem Cell Research & Therapy2014Vol. 5(1), pp. 25–25
Citations Over TimeTop 10% of 2014 papers
Danielle Jaqueta Barberini, Natália Pereira Paiva Freitas, Mariana Sartori Magnoni, Leandro Maia, Amanda J. Listoni, Marta Cristina Thomas Heckler, Mateus José Sudano, Márjorie de Assis Golim, Fernanda da Cruz Landim‐Alvarenga, Rogério Martins Amorim
Abstract
The BM, AT and UC are feasible sources for harvesting equine MSCs, and their immunophenotypic and multipotency characteristics attained minimal criteria for defining MSCs. Due to the low expression of MHC-II by MSCs, all of the sources could be used in clinical trials involving allogeneic therapy in horses. However, the BM-MSCs and AT-MSCs showed fastest ''in vitro'' differentiation and AT-MSCs showed highest cell growth until third passage. These findings suggest that BM and AT may be preferable for cell banking purposes.
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