New fat-derived products for treating skin-induced lesions of scleroderma in nude mice
Stem Cell Research & Therapy2014Vol. 5(6), pp. 138–138
Citations Over TimeTop 15% of 2014 papers
Nicolas Serratrice, Laurie Bruzzese, Jérémy Magalon, Julie Véran, Laurent Giraudo, Houssein Aboudou, Djaffar Ould-Ali, Pierre Nguyen, Olivier Bausset, Aurélie Daumas, Dominique Casanova, B. Granel, Lucile Andrac‐Meyer, Florence Sabatier, G. Magalon
Abstract
All tested substances were effective in treating skin-induced lesions of scleroderma with different levels of fibrosis and vascular improvement; MF derived products are more stable and SVF demonstrated better pro-angiogenic effects. The observed efficacy of this combination of products in the animal model provides a rationale for potential clinical applications to treat human disease.
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