Cognitive performance and functional outcomes of carriers of pathogenic copy number variants: analysis of the UK Biobank
The British Journal of Psychiatry2019Vol. 214(5), pp. 297–304
Citations Over TimeTop 1% of 2019 papers
Kimberley Kendall, Matthew Bracher‐Smith, H Fitzpatrick, Amy Lynham, Elliott Rees, Valentina Escott‐Price, Michael J. Owen, Michael O’Donovan, James Walters, George Kirov
Abstract
CNVs implicated in neurodevelopmental disorders, including schizophrenia, are associated with cognitive deficits, even among unaffected individuals. These deficits may be subtle but CNV carriers have significant disadvantages in educational attainment and ability to earn income in adult life.Declaration of interestNone.
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