Tetrapyrrole Metabolism inArabidopsis thaliana

Citations Over TimeTop 10% of 2011 papers

Abstract

Higher plants produce four classes of tetrapyrroles, namely, chlorophyll (Chl), heme, siroheme, and phytochromobilin. In plants, tetrapyrroles play essential roles in a wide range of biological activities including photosynthesis, respiration and the assimilation of nitrogen/sulfur. All four classes of tetrapyrroles are derived from a common biosynthetic pathway that resides in the plastid. In this article, we present an overview of tetrapyrrole metabolism in Arabidopsis and other higher plants, and we describe all identified enzymatic steps involved in this metabolism. We also summarize recent findings on Chl biosynthesis and Chl breakdown. Recent advances in this field, in particular those on the genetic and biochemical analyses of novel enzymes, prompted us to redraw the tetrapyrrole metabolic pathways. In addition, we also summarize our current understanding on the regulatory mechanisms governing tetrapyrrole metabolism. The interactions of tetrapyrrole biosynthesis and other cellular processes including the plastid-to-nucleus signal transduction are discussed.

Related Papers

• → Bilateral Communication between Plastid and the Nucleus: Plastid Protein Import and Plastid-to-Nucleus Retrograde Signaling(2010)36 cited
• → Origin and Evolution of Plastids: Genomic View on the Unification and Diversity of Plastids(2007)35 cited
• → Porphyrin and heme synthesis(2019)16 cited
• → Origin and Evolution of Plastids: Genomic View on the Unification and Diversity of Plastids(2006)2 cited
• → OBSERVATIONS ON THE ORIGIN AND MULTIPLICATION OF PLASTIDS(1962)16 cited