Induction of CD8+T-Cell Responses Against Novel Glioma–Associated Antigen Peptides and Clinical Activity by Vaccinations With α-Type 1 Polarized Dendritic Cells and Polyinosinic-Polycytidylic Acid Stabilized by Lysine and Carboxymethylcellulose in Patients With Recurrent Malignant Glioma
Journal of Clinical Oncology2010Vol. 29(3), pp. 330–336
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Hideho Okada, Paweł Kaliński, Ryo Ueda, Aki Hoji, Gary Kohanbash, Teresa E. Donegan, Arlan Mintz, Johnathan A. Engh, David L. Bartlett, Charles K. Brown, Herbert J. Zeh, Matthew P. Holtzman, Todd A. Reinhart, Theresa L. Whiteside, Lisa H. Butterfield, Ronald L. Hamilton, Douglas M. Potter, Ian F. Pollack, Andres Μ. Salazar, Frank S. Lieberman
Abstract
These data support safety, immunogenicity, and preliminary clinical activity of poly-ICLC-boosted αDC1-based vaccines.
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