TRACEBACK: Testing of Historical Tubo-Ovarian Cancer Patients for Hereditary Risk Genes as a Cancer Prevention Strategy in Family Members
Journal of Clinical Oncology2022Vol. 40(18), pp. 2036–2047
Citations Over TimeTop 13% of 2022 papers
Rachel Delahunty, Linh T. Nguyen, Stuart Craig, Belinda Creighton, Dinuka Ariyaratne, Dale W. Garsed, Elizabeth L. Christie, Sián Fereday, Lesley Andrews, Alexandra Lewis, Sharne Limb, Ahwan Pandey, Joy Hendley, Nadia Traficante, Natalia Carvajal, Amanda B. Spurdle, Bryony A. Thompson, Michael T. Parsons, Victoria Beshay, Mila Volcheck, Timothy Semple, Richard Lupat, Kenneth Doig, Jiaan Yu, Xiaohong Chen, Anna Marsh, Christopher G. Love, Sanela Bilic, Maria Beilin, Cassandra Nichols, Christina M. Greer, Yeh Chen Lee, Susan Gerty, Lynette Gill, Emma M. Newton, Julie A. Howard, Rachel Williams, Christie Norris, Andrew N. Stephens, Erin Tutty, Courtney Smyth, Shona O’Connell, Thomas W. Jobling, Colin J.R. Stewart, Adeline Tan, Stephen B. Fox, Nicholas Pachter, Jason Li, Jason Ellul, Gisela Mir Arnau, Mary‐Anne Young, Louisa G. Gordon, Laura Forrest, Marion Harris, Karen Livingstone, Jane Hill, Georgia Chenevix‐Trench, Paul A. Cohen, Penelope M. Webb, Michael Friedländer, Paul A. James, David D.L. Bowtell, Kathryn Alsop, on behalf of The Australian Ovarian Cancer Study, Ovarian Cancer Prognosis and Lifestyle Study and the TRACEBACK Study
Abstract
We overcame ethical and logistic challenges to demonstrate that retrospective genetic testing to identify PVs in previously untested deceased probands with TOC is feasible. Understanding reasons for a family member's decision to accept or decline a referral will be important for guiding future TRACEBACK projects.
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