Biomarkers Improving Genetic and Metastatic Disease Prediction in Paraganglioma: Insights From a Prospective Study
The Journal of Clinical Endocrinology & Metabolism2024Vol. 110(8), pp. 2193–2204
Citations Over TimeTop 14% of 2024 papers
Tom Drossart, Alexandre Buffet, Ali Janbain, Chris Ottolenghi, Laurence Amar, Rossella Libé, D. Drui, Charlotte Lussey‐Lepoutre, Maxence Mancini, Timgad Lounis, Armelle Arnoux, Tchao Méatchi, Jérôme Bertherat, Nelly Burnichon, Judith Favier, Anne‐Paule Gimenez‐Roqueplo, COMETE-TACTIC Study Group, Anne‐Paule Gimenez‐Roqueplo, Laurence Amar, Gilles Manceau, Anne-Marie Madjalian, Anne‐Laure Faucon, Erika Cornu, Sandrine Laboureau-Soares, Ingrid Allix, F. Illouz, Fairouz Lalmi, Aline Gauthier, Belaïd Sekour, Hervé Lefèbvre, Anne-Françoise Cailleux, Romain Le Bolc'h, Hind Berrahmoune, E. Sonnet, Laurent Doucet, Vincent Joulin, Françoise Borson‐Chazot, Hélène Lasolle, Jean‐Christophe Lifante, L. Maillard, Myriam Decaussin‐Petrucci, Armelle Delahaye, Marie Batisse‐Lignier, Damien Bouvier, Catherine Godfraind, Olivier Chabre, Philippe Chaffanjon, Nathalie Stürm, Gabriel Schummer, Justine Cristante, L. Nasse, Flora Fassio, I. Raingeard, Emmanuelle Gall, L. Zerkowski, Anne‐Marie Dupuy, Frédérique Llorcy, D. Drui, M. Le Bras, Anne-Laure Fournier, Ester Landau, E. Barrak, Bertrand Cariou, Violette Dierry, Audrey Ernould, Eric Mirallié, C. Caillard, Christophe Ferron, Karine Renaudin, Cécile Girard, Jérôme Bertherat, Laurence Guignat, Lionel Groussin, Guillaume Assié, Rossella Libé, Anne Jouinot, Meriama Saidi, Karine Perlemoine, Mathilde Sibony, Benoît Terris, Béatrice Parfait, Charlotte Lussey‐Lepoutre, Suzanne Laroche, Christel Jublanc, Virginie Grouthier, Christophe Trésallet, Pr F Ménégaux, Gabrielle Deniziaut, G. Hervé, Isabelle Brochériou, Jean-Yves Delattre, Inès Detrait, Antoine Tabarin, Magalie Haissaguerre, Amandine Galioot, Marie Puerto, Isabelle Guilhem, Agathe Guénégo, Annabelle Esvant, A. Manunta, Bernard Goichot, Michel Vix, Didier Mutter, Hervé Lang, Pietro Addeo, P. Pierre, Lise Crinière, Serge Guyétant, Gaëlle Fromont, F. Bruyère, B. Faivre d’Arcier, Céline Bourbao, Éric Baudin, Sophie Giraud, Julien Hadoux, Livia Lamartina
Abstract
Circulating miR-483-5p, plasma succinate, TERT promoter methylation, and SDHB immunostaining are valuable for PPGL risk stratification. Combining biomarkers with clinical data provides excellent diagnostic accuracy for metastatic patients (AUC-ROC 0.97, 95%CI 0.93-1).
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