A Reverse J-Shaped Association of All-Cause Mortality with Serum 25-Hydroxyvitamin D in General Practice: The CopD Study
The Journal of Clinical Endocrinology & Metabolism2012Vol. 97(8), pp. 2644–2652
Citations Over TimeTop 1% of 2012 papers
Darshana Durup, Henrik L. Jørgensen, Jane Christensen, Peter Schwarz, Anne‐Marie Heegaard, Bent Lind
Abstract
In this study from the general practice sector, a reverse J-shaped relation between the serum level of 25(OH)D and all-cause mortality was observed, indicating not only a lower limit but also an upper limit. The lowest mortality risk was at 50-60 nmol/liter. The study did not allow inference of causality, and further studies are needed to elucidate a possible causal relationship between 25(OH)D levels, especially higher levels, and mortality.
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