ATP-dependent chromatin remodeling during mammalian development
Development2016Vol. 143(16), pp. 2882–2897
Citations Over TimeTop 10% of 2016 papers
Abstract
Precise gene expression ensures proper stem and progenitor cell differentiation, lineage commitment and organogenesis during mammalian development. ATP-dependent chromatin-remodeling complexes utilize the energy from ATP hydrolysis to reorganize chromatin and, hence, regulate gene expression. These complexes contain diverse subunits that together provide a multitude of functions, from early embryogenesis through cell differentiation and development into various adult tissues. Here, we review the functions of chromatin remodelers and their different subunits during mammalian development. We discuss the mechanisms by which chromatin remodelers function and highlight their specificities during mammalian cell differentiation and organogenesis.
Related Papers
- → Mechanisms of thymus organogenesis and morphogenesis(2011)296 cited
- → Organogenesis in Vitro as a Developmental Process(1988)92 cited
- → Developmental and Structural Aspects of Root Organogenesis(1999)4 cited
- Effects of polyamines on organogenesis and somatic embryogenesis of Lycium barbarum calli.(2001)
- → Embryotoxic Action of β-Aminopropionitrile During Early Organogenesis in Rats(1987)1 cited