Cell adhesion and chondrogenesis in brachypod mouse limb mesenchyme: fragment fusion studies
Development1978Vol. 48(1), pp. 161–168
Abstract
This study is a continuing investigation of the effect of the brachypod mouse mutation on cell interactions and chondrogenesis during early limb development. In this report, cell adhesiveness was assessed in fused fragments of brachypod and normal limb-bud mesenchyme. Examination of the interface of fused distal postaxial limb fragments show brachypod limb mesenchyme to be more adhesive than normal limb mesenchyme. Chondrogenesis within brachypod fragments is delayed and less extensive than in normal fragments. In addition, chondrogenesis within normal fragments is not affected by the juxtaposition of the brachypod fragment, and vice versa.
Related Papers
- → SF/HGF is a mediator between limb patterning and muscle development(1999)97 cited
- → The expression of Fat-1 cadherin during chick limb development(2007)17 cited
- → Ectoderm-Mesenchyme and Mesenchyme-Mesenchyme Interactions Regulate Msx-1 Expression and Cellular Differentiation in the Murine Limb Bud(1995)104 cited
- → Multiple Digit Formation inXenopusLimb Bud Recombinants(1998)27 cited
- Molecular and Cellular Mechanisms Whereby the Apical Ectodermal Ridge (AER), Via Wnt5a, Mediates Directional Migration of the Adjacent Mesenchyme During Vertebrate Limb Development(2009)