1,4-Naphthoquinones: Some Biological Properties and Application
Citations Over TimeTop 1% of 2019 papers
Abstract
Over the past decade, a number of new 1,4-naphthoquinones have been isolated from natural sources and new 1,4-naphthoquinones with diverse structural features have been synthesized. Cardioprotective, anti-ischemic, hepatoprotective, neuroprotective and some other new properties were found for these compounds; their role in protecting against neurodegenerative diseases has been established. Their anti-inflammatory, antimicrobial and antitumor activities have been studied in more detail; new, previously unknown intracellular molecular targets and mechanisms of action have been discovered. Some compounds of this class are already being used as a medicinal drugs and some substances can be used as biochemical tools and probes for non-invasive detection of pathological areas in cells and tissues in myocardial infarction and neurodegenerative diseases using modern molecular imaging techniques.
Related Papers
- → Neuroprotective Properties of Chitosan and Its Derivatives(2010)165 cited
- → Neuroprotective effects of the survival promoting peptide Y-P30(2009)8 cited
- → Combinatorial techniques for enhancing neuroprotection(2010)10 cited
- → DETERMINING QUALITY REQUIREMENTS AT THE UNIVERSITIES TO IMPROVE THE QUALITY OF EDUCATION(2018)
- POTENTIAL NEUROPROTECTIVE EFFECTS OF HERBAL COMPOUNDS(2015)