IL-1β, IL-6, and RANTES as Biomarkers of Chikungunya Severity
PLoS ONE2009Vol. 4(1), pp. e4261–e4261
Citations Over TimeTop 1% of 2009 papers
Lisa F. P. Ng, Lisa F. P. Ng, Angela Chow, Yong-Jiang Sun, Dyan J. C. Kwek, Poh‐Lian Lim, Frederico Dimatatac, Lee Ching Ng, Lee Ching Ng, Eng Eong Ooi, Khar-Heng Choo, Zhisheng Her, Philippe Kourilsky, Yee‐Sin Leo
Abstract
This is the first comprehensive report on the production of cytokines, chemokines, and growth factors during acute Chikungunya virus infection. Using these biomarkers, we were able to distinguish between mild disease and more severe forms of Chikungunya fever, thus enabling the identification of patients with poor prognosis and monitoring of the disease.
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