Sequence Variants of Toll Like Receptor 4 and Late-Onset Alzheimer's Disease
PLoS ONE2012Vol. 7(12), pp. e50771–e50771
Citations Over TimeTop 20% of 2012 papers
Abstract
Sequence variants of TLR4 were associated with an increased risk of LOAD, especially in ApoE e4 non-carriers and in hypertensive patients. The combination of TLR4 rs1927907 and ApoE e4 significantly increased the screening sensitivity in identifying LOAD patients from 0.4 to 0.7.
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